Blood rune

Ironman verdict

At least 9 monsters drop it. The easiest is Dark wizard (level 9, 2/128); the best rate is Living rock patriarch (level 95), at Always, about 50 per kill. You can also make it yourself: it takes 77 Runecrafting and gives 10.5 Runecrafting XP, using Pure essence. There is one other recipe below. Other sources include Gnome Restaurant, Hero, Muddy chest and Essence impling, plus 4 more listed below. Making ten takes 10 × Pure essence and gives 105 Runecrafting XP. Reaching level 77 Runecrafting takes 1,475,581 XP in total; the Runecrafting calculator counts the actions and materials to any target, and the Runecrafting guide has the Ironman training route. 18 recipes use Blood rune, including Annakarl teleport (item), Basic potion cauldron and Bubbling potion cauldron. Blood rune is members-only. It is tradeable on normal accounts, but an Ironman cannot use the Grand Exchange or trade for it, so the sources on this page are the whole list. High Alchemy turns one into 110 coins, which is 440 less than the shop price, so buying it to alch does not pay.